{"id":2613,"date":"2026-05-22T17:50:26","date_gmt":"2026-05-22T13:50:26","guid":{"rendered":"https:\/\/www.sureshdinakaran.com\/blog\/?p=2613"},"modified":"2026-05-22T17:50:49","modified_gmt":"2026-05-22T13:50:49","slug":"placebos-dont-prove-medicine-is-fake-they-prove-belief-is-powerful","status":"publish","type":"post","link":"https:\/\/www.sureshdinakaran.com\/blog\/2026\/05\/22\/placebos-dont-prove-medicine-is-fake-they-prove-belief-is-powerful\/","title":{"rendered":"Placebos don\u2019t prove medicine is fake. They prove belief is powerful"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>Way back in the early 90&#8217;s, from an overseas trip, I carried a tube of <span style=\"color: #ff0000;\"><em>Deep Heat<\/em><\/span> balm for my grandmother(which at that time was not available in India). She was suffering from severe arthritis pain for a long time. And her varicose veins were troubling her as well. Within a few days of my giving here the tube, she called to tell me that the pain had reduced considerably.<\/p>\n<p>&nbsp;<\/p>\n<p>At that time I had no idea about the power of the <span style=\"color: #ff0000;\"><em>placebo<\/em><\/span> effect. The fact that one of her favorite grandkids had got her this from abroad was enough for her to feel good and think the pain had subsided( <span style=\"color: #ff0000;\"><em>Deep Heat<\/em><\/span> for all its effectiveness does not work when you are battling arthritis | varicose veins).<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.akimbo.link\/\"><span style=\"color: #ff0000;\"><em>Seth Godin<\/em><\/span><\/a>, with his surgeon&#8217;s instinct for the uncomfortable obvious, puts his finger on it beautifully.<\/p>\n<p>&nbsp;<\/p>\n<p>We have two ways to explain the placebo. One says it&#8217;s a magic trick that disappears the moment you look at it directly \u2014 some mysterious force that defies physics and evaporates under rigorous testing. The other says: your brain believed something, and your body obeyed.<\/p>\n<p>&nbsp;<\/p>\n<blockquote><p><span style=\"color: #ff0000;\">&#8220;A placebo is a prompt for our subconscious to do the hard work of healing our body, increasing our satisfaction or maximizing our performance.&#8221;<\/span><\/p><\/blockquote>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><em>Godin<\/em><\/span> bets on the second. So do I. And so, quietly, does the evidence.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><span style=\"color: #ff0000;\"><em>Price Is The Yardstick Of Effectiveness: The Expensive Pill Problem<\/em><\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>Researchers at <span style=\"color: #ff0000;\"><em>MIT<\/em><\/span> gave two groups the same painkiller \u2014 same molecule, same dose. One group paid $2.50 per pill. The other paid ten cents. <span style=\"color: #ff0000;\"><em>The $2.50 group reported significantly more pain relief<\/em><\/span>. Nothing changed except the story wrapped around the pill.<\/p>\n<p>&nbsp;<\/p>\n<p>That&#8217;s not a quirk. That&#8217;s architecture. <span style=\"color: #ff0000;\"><em>Your subconscious runs on narrative<\/em><\/span>. It processes meaning, not molecules. And when the meaning is rich \u2014 premium packaging, a confident doctor, a name you can barely pronounce \u2014 it dispatches its best work.<\/p>\n<p>&nbsp;<\/p>\n<p>This is why the expensive placebo works better than the cheap one. Not because of what&#8217;s in it. <span style=\"color: #ff0000;\"><em>Because of what you believe about what&#8217;s in it<\/em><\/span>.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>Where We Have Been Missing The Wood For The Trees<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>We&#8217;ve been treating the placebo as a contaminant \u2014 the thing you have to subtract before you can see the &#8220;real&#8221; drug working. But what if it isn&#8217;t a contamination? What if it&#8217;s the point?<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMbkrev0810817\"><span style=\"color: #ff0000;\"><em>Fabrizio Benedetti<\/em><\/span><\/a>, one of the world&#8217;s foremost placebo researchers, has shown that <span style=\"color: #ff0000;\"><em>placebos trigger actual opioid release in the brain<\/em><\/span>. Real biochemistry. Not imagined comfort. The body doesn&#8217;t fake healing \u2014 it does healing, prompted by belief. The signal was always internal. The pill just rang the bell.<\/p>\n<p>&nbsp;<\/p>\n<p>Which means you&#8217;ve been walking around with a pharmacist inside you who only takes orders from your expectations.<\/p>\n<p>&nbsp;<\/p>\n<blockquote><p><span style=\"color: #ff0000;\">What you believe about what&#8217;s happening to you shapes what&#8217;s actually happening to you. This is not poetry. It&#8217;s physiology.<\/span><\/p><\/blockquote>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>What if the most powerful pharmacy in the world\u2026 is expectation?<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Science calls it the <span style=\"color: #ff0000;\"><em>placebo effect<\/em><\/span>.<br \/>\nModern marketing calls it <span style=\"color: #ff0000;\"><em>premium positioning<\/em><\/span>.<br \/>\nOur grandmothers called it \u201c<span style=\"color: #ff0000;\"><em>mind over matter<\/em><\/span>.\u201d<\/p>\n<p>&nbsp;<\/p>\n<p>And honestly? Grandma may have been onto something before neuroscience arrived with their research decks.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>We love explaining away placebos as frauds. \u201cOh, it\u2019s\u00a0just\u00a0placebo.\u201d<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>JUST?<\/p>\n<p>Imagine dismissing a force capable of changing blood pressure, pain thresholds, immune responses and performance levels because it didn\u2019t arrive wearing a Doctor&#8217;s lab coat.<\/p>\n<p>&nbsp;<\/p>\n<p>The real debate isn\u2019t whether placebos work. They do. Repeatedly. Astonishingly.<\/p>\n<p>&nbsp;<\/p>\n<p>The real debate is\u00a0<span style=\"color: #ff0000;\"><em>why<\/em><\/span>.<\/p>\n<p>&nbsp;<\/p>\n<p>One camp treats placebos like paranormal glitches \u2014 mysterious effects that disappear under rigorous testing and somehow sneak past the laws of biology.<\/p>\n<p>&nbsp;<\/p>\n<p>But there\u2019s another possibility. A far more interesting one.<\/p>\n<p>&nbsp;<\/p>\n<p>A placebo may simply be a trigger.<\/p>\n<p>&nbsp;<\/p>\n<p>A cue.<\/p>\n<p>&nbsp;<\/p>\n<p>A psychological ignition key that tells the subconscious:<\/p>\n<p>&nbsp;<\/p>\n<p>\u201cAlright buddy, healing mode. Let\u2019s go.\u201d<\/p>\n<p>&nbsp;<\/p>\n<p>And suddenly, the body starts cooperating with itself.<\/p>\n<p>&nbsp;<\/p>\n<p>Not magic. Coordination.<\/p>\n<p>&nbsp;<\/p>\n<p>Think about it.<\/p>\n<p>&nbsp;<\/p>\n<p>Why does expensive wine taste \u201cbetter\u201d in blind studies when people\u00a0<span style=\"color: #ff0000;\"><em>think<\/em><\/span>\u00a0it costs more?<\/p>\n<p>&nbsp;<\/p>\n<p>Why do athletes perform better wearing branded gear?<\/p>\n<p>&nbsp;<\/p>\n<p>Why do patients recover faster when doctors sound confident?<\/p>\n<p>&nbsp;<\/p>\n<p>Why does a child instantly feel safer when mom kisses a bruised elbow \u2014 despite absolutely zero medical transfer of healing lip molecules?<\/p>\n<p>&nbsp;<\/p>\n<p><strong><span style=\"color: #ff0000;\"><em>Expectation changes experience<\/em><\/span>. <span style=\"color: #ff0000;\"><em>Belief alters biology. Meaning modifies outcomes<\/em><\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>That\u2019s not pseudoscience. That\u2019s <span style=\"color: #ff0000;\"><em>humanity<\/em><\/span>.<\/p>\n<p>&nbsp;<\/p>\n<p>In one famous study, patients with knee pain improved after\u00a0<span style=\"color: #ff0000;\"><em>fake surgery<\/em><\/span>. Surgeons made incisions, pretended to operate and stitched them back up. Many patients reported relief comparable to actual procedures.<\/p>\n<p>&nbsp;<\/p>\n<p>Pause for a second.<\/p>\n<p>&nbsp;<\/p>\n<p>Their bodies responded not to the surgery\u2026<\/p>\n<p>&nbsp;<\/p>\n<p>\u2026but to the\u00a0<span style=\"color: #ff0000;\"><em>story<\/em><\/span>\u00a0of surgery.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>Which should terrify and inspire us equally<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Because if the mind can manufacture healing\u2026 it can also manufacture suffering.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><em>Nocebo<\/em><\/span> is placebo\u2019s evil twin. Tell people a harmless pill causes headaches and many will develop headaches. Give employees a terrifying economic forecast and productivity drops before anything actually changes.<\/p>\n<p>&nbsp;<\/p>\n<p>We don\u2019t merely experience reality. <em><span style=\"color: #ff0000;\">We experience our interpretation of reality. <\/span><\/em><span style=\"color: #ff0000;\"><em><strong>Your subconscious is always listening. So, Choose your scripts carefully.<\/strong><\/em><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>And suddenly, this isn\u2019t about medicine anymore<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>It\u2019s about leadership. Parenting. Branding. Relationships. Performance. Culture.<\/p>\n<p>&nbsp;<\/p>\n<p>A great teacher is partly a placebo.<br \/>\nSo is a charismatic leader.<br \/>\nSo is a luxury brand.<br \/>\nSo is confidence itself.<\/p>\n<p>&nbsp;<\/p>\n<p>All of them whisper the same message to the subconscious: \u201c<span style=\"color: #ff0000;\"><em>You can do more than you think.\u201d<\/em><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><em><strong>And often\u2026we can<\/strong><\/em><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Now before the rationalists begin foaming at the mouth \u2014 no, placebos are <span style=\"color: #ff0000;\"><strong><em>NOT<\/em><\/strong><\/span> substitutes for antibiotics, surgery or actual treatment.<\/p>\n<p>&nbsp;<\/p>\n<p>But dismissing them entirely is equally foolish.<\/p>\n<p>&nbsp;<\/p>\n<p>Because the placebo effect reveals something profound:<\/p>\n<p>&nbsp;<\/p>\n<p>Humans are not machines responding only to chemistry.<br \/>\nWe are meaning-making creatures responding to narrative, expectation and belief.<\/p>\n<p>&nbsp;<\/p>\n<p>Which means the stories we tell ourselves matter enormously.<\/p>\n<p>&nbsp;<\/p>\n<p>Tell yourself you\u2019re broken long enough, and the body listens.<\/p>\n<p>&nbsp;<\/p>\n<p>Tell yourself recovery is possible, and the body often joins the negotiation.<\/p>\n<p>&nbsp;<\/p>\n<p>That\u2019s not mystical.<\/p>\n<p>&nbsp;<\/p>\n<p>That\u2019s deeply biological.<\/p>\n<p>&nbsp;<\/p>\n<p>So perhaps the future of healing isn\u2019t choosing between science and belief.<\/p>\n<p>&nbsp;<\/p>\n<p>Perhaps <span style=\"color: #ff0000;\"><em>it\u2019s understanding how belief itself becomes biology<\/em><\/span>.<\/p>\n<p>&nbsp;<\/p>\n<p>And maybe the biggest placebo of all\u2026<span style=\"color: #ff0000;\"><em>is thinking the mind has no power over the body.<\/em><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>Now It Can Be Told: Our Brain Is The Most Underutilized Pharmacy On Earth<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><strong><em>Expensive Placebo. Cheap Placebo<\/em><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><em>Placebos are the strange currency of belief<\/em><\/span>. Dress the same sugar pill in a gold box, hand it to someone in a white coat, and watch confidence climb. Wrap it in a clinic\u2019s logo, price it like a miracle, and people swear the world is brighter. Call it \u201cancient protocol,\u201d type it in Helvetica on a glossy label, and boom \u2014 value materializes.<\/p>\n<p>&nbsp;<\/p>\n<p>Now for the real magic: the pill didn\u2019t change. the story did. <span style=\"color: #ff0000;\"><em>The placebo is less a mysterious force and more a prompt<\/em> <\/span>\u2014 one that nudges our subconscious to do the heavy lifting. That prompt can be dressed up in Gucci or shoved into a paper cup. <span style=\"color: #ff0000;\"><em>What matters is the story we believe<\/em><\/span>.<\/p>\n<p>&nbsp;<\/p>\n<p>Which would you choose \u2014 champagne hope or roadside solace \u2014 if both made you feel better?<\/p>\n<p>&nbsp;<\/p>\n<p>We love to ask whether expensive placebos are \u201cbetter\u201d because we want a simple answer: pay more, feel more. The messy truth is more useful. <span style=\"color: #ff0000;\"><em>Price and polish are amplifiers, not creators<\/em><\/span>. They tune the volume of the inner orchestra that already knows how to play.<\/p>\n<p>&nbsp;<\/p>\n<p>Picture two sprinters. One has a state-of-the-art pair of shoes; the other ties on an old, trusted pair and hears their coach whisper, \u201cThese are winners.\u201d The one with the glossy shoes might sprint faster \u2014 but only because the shiny shoes convinced their brain there\u2019s an edge. Or think of a colleague\u2019s LinkedIn post about a \u201ctransformational\u201d coaching program \u2014 same techniques you learned years ago, served with artful copy and a designer certificate. People sign up, feel transformed, and tweet grateful receipts. The practice didn\u2019t change. The frame did.<\/p>\n<p>&nbsp;<\/p>\n<p><em><strong><span style=\"color: #ff0000;\">Why this matters for creators and leaders<\/span><\/strong><\/em><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ff0000;\"><em>Story is infrastructure<\/em><\/span>. Your brand, the rituals you create, the language you use \u2014 they\u2019re scaffolding for the placebo prompt. So when you design experiences, you\u2019re either empowering people\u2019s own healing and performance or you\u2019re leaving it to chance.<\/p>\n<p>&nbsp;<\/p>\n<p>The most expensive placebo is waiting for someone else to fix you.<br \/>\nThe cheap one is realizing you already have the remote control. You\u2019ve just been pressing the wrong button.<\/p>\n<p>&nbsp;<\/p>\n<p>PS: If this blog inspires you to engage with me, it will be a pleasure to hear from you on suresh@groupisd.com<\/p>\n<p>&nbsp;<\/p>\n<p id=\"m_-5160795363325946089m_-835688063227211756m_147720276043425337m_-1304497621410638294m_8749466489762166908m_-6511489753078034510ember322\"><strong><em>PS:\u00a0<\/em><\/strong>On a completely different note,\u00a0I am taking the liberty to share here that my other blog\u00a0<a href=\"https:\/\/www.linkedin.com\/build-relation\/newsletter-follow?entityUrn=7331490759587627008\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.linkedin.com\/build-relation\/newsletter-follow?entityUrn%3D7331490759587627008&amp;source=gmail&amp;ust=1779544122197000&amp;usg=AOvVaw1IUh45HxobtZj-GaB8ekgK\"><strong><em>SOHB(State Of The Heart Branding) Story\u00a0<\/em><\/strong><\/a>is now a Podcast as well<em>.\u00a0<\/em>You can access it on these links below:<\/p>\n<ul>\n<li><a href=\"https:\/\/profile.dailyhunt.in\/SOHBStory\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/profile.dailyhunt.in\/SOHBStory&amp;source=gmail&amp;ust=1779544122198000&amp;usg=AOvVaw0Y7FLQfBvl5LEM4kxj4qRl\">https:\/\/profile.dailyhunt.in\/<wbr \/>SOHBStory<\/a><\/li>\n<li>Instagram:\u00a0<a href=\"https:\/\/www.instagram.com\/sohb.story\/\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.instagram.com\/sohb.story\/&amp;source=gmail&amp;ust=1779544122198000&amp;usg=AOvVaw3uabQXiG7D9DITjoJqbT0H\">https:\/\/www.instagram.com\/<wbr \/>sohb.story\/<\/a><\/li>\n<li>YouTube:\u00a0<a href=\"https:\/\/www.youtube.com\/@SOHBStory\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.youtube.com\/@SOHBStory&amp;source=gmail&amp;ust=1779544122198000&amp;usg=AOvVaw1XRQSrALi7M4x6grMvOt8J\">https:\/\/www.youtube.com\/@<wbr \/>SOHBStory<\/a><\/li>\n<li>Spotify Creators:\u00a0<a href=\"https:\/\/creators.spotify.com\/pod\/profile\/sobh-story\/\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/creators.spotify.com\/pod\/profile\/sobh-story\/&amp;source=gmail&amp;ust=1779544122198000&amp;usg=AOvVaw1Iv46bgih8bfFEsC89EoaJ\">https:\/\/creators.spotify.com\/<wbr \/>pod\/profile\/sobh-story\/<\/a><\/li>\n<li>Spotify:\u00a0<a href=\"https:\/\/open.spotify.com\/show\/3e4IAeGuwELReOcWJ4Csvj?si=1c1f6cb320644d30\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/open.spotify.com\/show\/3e4IAeGuwELReOcWJ4Csvj?si%3D1c1f6cb320644d30&amp;source=gmail&amp;ust=1779544122198000&amp;usg=AOvVaw0Lzw54pprTuZEqrHmKOmwA\">https:\/\/open.spotify.com\/show\/<wbr \/>3e4IAeGuwELReOcWJ4Csvj?si=<wbr \/>1c1f6cb320644d30<\/a><\/li>\n<li>Amazon Music:\u00a0<a href=\"https:\/\/music.amazon.com\/podcasts\/ab0afb48-e3d2-4cf7-8279-7392d97d1bcd\/sohb-state-of-the-heart-branding-story\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/music.amazon.com\/podcasts\/ab0afb48-e3d2-4cf7-8279-7392d97d1bcd\/sohb-state-of-the-heart-branding-story&amp;source=gmail&amp;ust=1779544122198000&amp;usg=AOvVaw3dVwBGuzO1ZFOtvGoIPuSC\">https:\/\/music.amazon.com\/<wbr \/>podcasts\/ab0afb48-e3d2-4cf7-<wbr \/>8279-7392d97d1bcd\/sohb-state-<wbr \/>of-the-heart-branding-story<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Way back in the early 90&#8217;s, from an overseas trip, I carried a tube of Deep Heat balm for my grandmother(which at that time was not available in India). She was suffering from severe arthritis pain for a long time. And her varicose veins were troubling her as well. Within a few days of &hellip; <a href=\"https:\/\/www.sureshdinakaran.com\/blog\/2026\/05\/22\/placebos-dont-prove-medicine-is-fake-they-prove-belief-is-powerful\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Placebos don\u2019t prove medicine is fake. They prove belief is powerful&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2613","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/posts\/2613","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/comments?post=2613"}],"version-history":[{"count":2,"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/posts\/2613\/revisions"}],"predecessor-version":[{"id":2615,"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/posts\/2613\/revisions\/2615"}],"wp:attachment":[{"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/media?parent=2613"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/categories?post=2613"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sureshdinakaran.com\/blog\/wp-json\/wp\/v2\/tags?post=2613"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}